产品货号：
JN2071
中文名称：
重组SARS-CoV-2 Guanine-N7 methyltransferase(His标签)
英文名称：
Recombinant SARS-CoV-2 Guanine-N7 methyltransferase (N-6His)
产品规格：
10μg|50μg
发货周期：
1～3天
产品价格：
询价
本制品由E.coli表达系统制备，目的基因编码表达SARS-CoV-2 Guanine-N7 methyltransferase(Ala1-Gln527)，N端包含一个6*His标签。
Accession#:YP_009725309.1
蛋白别称：SARS-CoV 2 nsp14；SARS-CoV 2 ExoN；Guanine-N7 methyltransferase
贮存液：PBS，10% Glycerol，pH7.4，0.2μm过滤
分子量：62.9kDa
实测分子量：60kDa（还原条件下）
纯度：＞85%（还原SDS-PAGE）
保存条件：-20℃，可稳定保存6个月，应避免反复冻融。
背景资料：
The nonstructural protein 14(NSP14) of SARS-CoV-2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase).Nsp14 of coronaviruses two different activities:an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity.It may be involved in the proof-reading ability during the viral RNA replication and transcription.GTP,dGTP as well as cap analogs GpppG,GpppA and m7GpppG could be methylated by nsp14.positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps).SARS-CoV 2 polyproteins incorporate 16 protein domains (nsps).The putative non-structural protein 2 (nsp2) of SARS-CoV plays an important role in viral transcription and replication,and is an attractive target for anti-SARS drug development.
相关搜索：重组SARS-CoV-2 Guanine-N7 methyltransferase(His标签)，重组新型冠状病毒鸟嘌呤-N7甲基转移酶，重组新冠病毒鸟嘌呤-N7甲基转移酶，重组SARS-CoV-2鸟嘌呤-N7甲基转移酶，重组SARS-CoV-2 NSP14蛋白
Accession#:YP_009725309.1
蛋白别称：SARS-CoV 2 nsp14；SARS-CoV 2 ExoN；Guanine-N7 methyltransferase
贮存液：PBS，10% Glycerol，pH7.4，0.2μm过滤
分子量：62.9kDa
实测分子量：60kDa（还原条件下）
纯度：＞85%（还原SDS-PAGE）
保存条件：-20℃，可稳定保存6个月，应避免反复冻融。
背景资料：
The nonstructural protein 14(NSP14) of SARS-CoV-2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase).Nsp14 of coronaviruses two different activities:an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity.It may be involved in the proof-reading ability during the viral RNA replication and transcription.GTP,dGTP as well as cap analogs GpppG,GpppA and m7GpppG could be methylated by nsp14.positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps).SARS-CoV 2 polyproteins incorporate 16 protein domains (nsps).The putative non-structural protein 2 (nsp2) of SARS-CoV plays an important role in viral transcription and replication,and is an attractive target for anti-SARS drug development.
相关搜索：重组SARS-CoV-2 Guanine-N7 methyltransferase(His标签)，重组新型冠状病毒鸟嘌呤-N7甲基转移酶，重组新冠病毒鸟嘌呤-N7甲基转移酶，重组SARS-CoV-2鸟嘌呤-N7甲基转移酶，重组SARS-CoV-2 NSP14蛋白